Ketamine - Alcohol and Drug Foundation

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Ketamine is a medicine used by doctors and vets as a sedative for short procedures. It changes how your brain gets messages of pain. A form of ketamine is occasionally used as an antidepressant at some specialist clinics.
Some other names for ketamine are:
Ketamine is also sold illegally for its hallucinogenic 'high' effect. It usually looks like a white powder. The powder can be made into tablets or dissolved into a clear liquid.
Ketamine can be:
It's hard to know how much ketamine is in the powder you buy. It might be cut (mixed) with another substance.
Ecstasy sometimes contains ketamine. It can also be used to spike drinks.
Ketamine starts to work within 30 seconds to 20 minutes, depending on how it's taken. The effects of the drug can last for 45 minutes to 3 hours and can include feeling happy and relaxed.
Ketamine users may experience 'falling into a k-hole', where you feel disassociated or unattached from your body.
People who take ketamine can also hallucinate. It changes your perception of reality. You might see, hear, smell or taste things that don't exist. Or you may see things differently to how they really are.
Ketamine may cause:
Ketamine can also cause unwanted side effects like:
Ketamine affects people differently based on:
People coming off ketamine may have symptoms for 4 to 6 days, including:
If you go into a 'k-hole' you might harm yourself.
A ketamine overdose can cause:
These can be fatal (cause death).
Signs that someone has overdosed on ketamine include:
Try healthdirect's Symptom Checker to get advice on when to seek help for symptoms and issues related drug use.
People who use ketamine long-term can get:
Regular users of ketamine are also more likely to have social, work and financial problems.
Find out more about how drugs and alcohol can impact your health.
Ketamine bladder syndrome is a painful condition that causes ulcers in your bladder. This leads to incontinence and needs long term treatment. Ketamine bladder syndrome can lead to kidney problems.
Taking ketamine with alcohol, heroin or other opiates is dangerous. It can slow your nervous system and your breathing. This can be fatal (cause death).
Taking ketamine with other drugs also puts strain on your body and leads to a fast heart rate. These other drugs include:
If you buy ketamine from a new dealer, it may have different effects to what you expect. There's no good way to know how strong it might be.
There are now pill testing or drug checking centres in some parts of Australia. These services can let you know if a drug is contaminated or very strong.
Injecting ketamine is more dangerous than swallowing it.
If you inject ketamine, you can reduce your risk of blood-borne disease by attending a Needle and Syringe Program (NSP).
An NSP service gives clean needles or syringes to people who inject drugs. It's sometimes called a 'needle exchange'.
Needle and syringe programs often operate from pharmacies.
You can also find a local needle and syringe program using the healthdirect Service Finder.
People who regularly use ketamine can become tolerant. This means that you need more of the drug to get the same effects.
You can also develop an addiction to ketamine. This is when you spend a lot of time thinking about the next time you can use the drug and how to get more. Some users may feel like they need the drug just to get through the day.
Addiction or dependence can impact your life, work and relationships. You may find it difficult to stop using ketamine or to control how much you use.
If you stop using ketamine after regular use, you might crave the drug.
Stopping ketamine can be difficult. If you are having problems with quitting, talk to your doctor. They can help you find ways to manage withdrawal symptoms, and explain treatment options, such as:
For information and advice about ketamine you can try one of the support services below.
You can also call the healthdirect helpline on 1800 022 222 (known as NURSE-ON-CALL in Victoria). A registered nurse is available to speak with you 24 hours a day, 7 days a week.
Visit the Health Translations Victoria website. The 'Where can I get help when alcohol or drugs are a problem?' video is available in different languages.
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Last reviewed: February 2025



